What you should know when taking NIASPAN
If a low-fat diet and exercise are not doing enough to improve your cholesterol levels, your doctor may prescribe NIASPAN®.
People who begin taking NIASPAN commonly report a treatment effect doctors refer to as flushing. Flushing occurs as blood vessels expand, increasing the flow of blood to the surface of the skin. Many people describe flushing as warmth, redness, itching, or tingling of the skin.
This presentation shows more about what you may experience and offers simple tips to help manage certain common treatment effects.
What you should remember
Although flushing does not affect everyone in the same way, there are some things you should keep in mind.
- If you are experience flushing and need to stand, take your time.
- If you wake up at night because of flushing, get up slowly, especially if you:
— feel dizzy or faint
— take blood pressure medicines
- The flushing may lessen over time with consistent use as your body adjusts to the medication.
Talk with your doctor about symptoms
Some patients may mistake the symptoms of flushing with those of a heart attack. Talk to your doctor about how these symptoms differ from one another.
Additional Safety Information
Additional common side effects of NIASPAN include headache, diarrhea, nausea, vomiting, increased cough, and itching.
Blood tests are needed before and during treatment with NIASPAN to check for liver problems.
Contact a health care provider if serious side effects such as unexplained muscle pain, tenderness or weakness develop. The risk of these side effects may be higher when lovastatin or simvastatin are taken with NIASPAN.
Tell your health care provider if you have a history of gout, drink large amounts of alcohol, or if you are diabetic or experience increases in blood sugar.
Deciding if NIASPAN is right for you
Only your doctor can decide if NIASPAN should be a part of your treatment plan. Some medicines should not be taken with NIASPAN. Tell your healthcare provider about all the prescription and non-prescription medicines you take, including:
- Aspirin
- Cholesterol medication
- Blood pressure medication
- Blood sugar medication
- Anticoagulants, also known as blood thinners
- Any products containing niacin or nicotinamide
Important Safety Information and Uses You Should Know About
NIASPAN® (niacin extended-release tablets)
IMPORTANT SAFETY INFORMATION for NIASPAN
NIASPAN is not for people with liver problems, stomach ulcers, serious bleeding problems, or those allergic to any product ingredient.
Severe liver damage can occur when switching to a long-acting niacin (NIASPAN) from immediate-release niacin. Do not switch between forms of niacin without talking to your health care provider.
Tell your health care provider about any unexplained muscle pain, tenderness, or weakness, as this could be a sign of a serious side effect. This risk may be increased when NIASPAN is taken with a statin, particularly in the elderly, diabetics, and those with kidney or thyroid problems.
NIASPAN should be used with caution if you consume large amounts of alcohol and/or have a past history of liver disease.
Your health care provider should do blood tests before and during treatment to check liver enzyme levels, as these may increase with treatment.
Tell your health care provider if you have kidney problems, or a history of gout. NIASPAN may cause an increase in uric acid levels.
NIASPAN may cause an increase in blood sugar levels. If you have diabetes, check your blood sugar levels more frequently during the first few months or with NIASPAN dose changes.
The most common side effects with NIASPAN are flushing, headache, diarrhea, nausea, vomiting, increased cough, and itching.
Flushing (warmth, redness, itching, and/or tingling of the skin) is a common side effect of niacin therapy that may get better after several weeks of consistent NIASPAN use. It may vary in severity and is more likely to happen when starting NIASPAN or during dose increases. Talk to your doctor about how the symptoms of flushing are different from symptoms of a heart attack. By dosing at bedtime, flushing will likely occur during sleep. If awakened by flushing, get up slowly, especially if feeling dizzy or faint, or taking blood pressure medications.
If you are taking another cholesterol medication called a bile acid-binding resin (e.g., colestipol, cholestyramine) along with NIASPAN, take these medicines at least 4 to 6 hours apart.
Some medicines should not be taken with NIASPAN. Tell your health care provider about all the medicines you take, including aspirin, any cholesterol medication, blood pressure medication, or blood thinner medication, or any products containing niacin or nicotinamide.
USES for NIASPAN® (niacin extended-release tablets)
NIASPAN is a prescription medication used along with diet when a low-cholesterol diet and exercise alone are not enough.
NIASPAN raises HDL ("good") cholesterol and lowers LDL ("bad") cholesterol and triglycerides in people with abnormal cholesterol levels.
NIASPAN is also used to lower the risk of heart attack in people who have had a heart attack and have high cholesterol.
In people with coronary artery disease and high cholesterol levels, NIASPAN, when used with a bile acid-binding resin (another cholesterol medicine), can slow down or lessen the build up of plaque (fatty deposits) in your arteries.
NIASPAN can be used in combination with lovastatin or simvastatin to improve abnormal cholesterol levels when taking NIASPAN, simvastatin, or lovastatin alone is not enough.
No additional benefit of NIASPAN on heart disease has been demonstrated when used with simvastatin or lovastatin over that shown for niacin, simvastatin, or lovastatin alone.
For more information, talk with your health care provider.
Please see the full Prescribing Information for NIASPAN and discuss it with your health care provider.
Reference: NIASPAN [package insert]. North Chicago, IL: Abbott Laboratories
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
If you cannot afford your medication, contact: www.pparx.org or call the toll-free phone number 1-888-4PPA-NOW (1-888-477-2669) for assistance.